What proportion of the offspring could you theoretically expect to be homozygous for the transgene if you mate two hemizygous parents?

Prepare for the AALAS LATG Test. Study with interactive flashcards and detailed multiple-choice questions, each with hints and explanations. Achieve your certification goals!

Multiple Choice

What proportion of the offspring could you theoretically expect to be homozygous for the transgene if you mate two hemizygous parents?

Explanation:
The important idea is that each parent with a single copy of the transgene can pass either the transgene allele or the normal allele to their offspring, with equal probability. Crossing two such parents (a transgene allele in one chromosome and a non-transgene allele on the other) follows a simple 1:2:1 genotypic pattern: TT (two transgene copies) : Tt (one copy) : tt (no copies) in a 1:2:1 ratio. That means 1 out of 4 offspring, or 25%, would be homozygous for the transgene.

The important idea is that each parent with a single copy of the transgene can pass either the transgene allele or the normal allele to their offspring, with equal probability. Crossing two such parents (a transgene allele in one chromosome and a non-transgene allele on the other) follows a simple 1:2:1 genotypic pattern: TT (two transgene copies) : Tt (one copy) : tt (no copies) in a 1:2:1 ratio. That means 1 out of 4 offspring, or 25%, would be homozygous for the transgene.

Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy