The purchase order for obtaining animals must include which element to ensure compliance?

• A. Animal numbers approved by the researcher
• B. Species, strain, and number approved by the IACUC in protocol
• C. Species and color
• D. Breed and vendor

Answer: (B)

The main idea is that procurement of animals must match what the IACUC has approved in the protocol. The protocol specifies exactly which animals may be used, including the species, the specific strain or line, and how many animals are allowed. A purchase order should reflect those same details so the institution stays in compliance with animal welfare regulations and can accurately track and justify animal use. If the order tried to bring in animals outside those approved parameters, it would require protocol amendments and additional IACUC approval, creating delays and potential compliance issues.

That’s why simply relying on numbers approved by the researcher isn’t sufficient—approval must come through the IACUC. Color isn’t a relevant factor for compliance, and breed or vendor details aren’t what the protocol uses to authorize use. The crucial elements are species, strain, and the number approved in the IACUC protocol.