The numbers of animals purchased by a researcher are usually tracked against which of these numbers?

• A. Species and specific numbers in the current research protocol approved by the IACUC
• B. Species and estimated numbers approved in the current research protocol approved by IACUC
• C. Estimate for species and numbers projected in the researcher's budget.
• D. Species and average number used by the researcher over the past five years

Answer: (A)

When managing animal use, the approved scope of a study is defined by the IACUC protocol, including the species and the exact number of animals permitted. Researchers track purchases and actual usage against those exact numbers in the current protocol to ensure compliance, avoid overuse, and maintain proper records for auditing and oversight. If more animals are needed or if the plan changes, any increase or modification must be approved through an IACUC amendment before it can be implemented.

Estimates, budgets, or historical averages do not establish the authorized limits for ongoing work, so they aren’t the basis for tracking. The protocol’s specified numbers are the binding reference for both welfare oversight and resource planning.