Lymphocytic choriomeningitis virus (LCMV) is a zoonotic organism which may infect mice and hamsters.

• A. True
• B. False
• C. Only mice
• D. Only hamsters

Answer: (A)

LCMV is a zoonotic virus that can infect more than one rodent species, which is why it matters in laboratory animal settings. Mice are the natural reservoir and most commonly associated with infection, and hamsters can also become infected when exposed to the virus or contaminated materials. The zoonotic nature means humans can acquire LCMV from infected rodents, highlighting the need for proper biosafety practices and colony management. Because transmission can occur via urine, droppings, or nesting materials, recognizing that the virus can involve both mice and hamsters supports why this statement is true.