In which of the following routes of administration, would a drug have the slowest rate of absorption into the bloodstream?

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Multiple Choice

In which of the following routes of administration, would a drug have the slowest rate of absorption into the bloodstream?

Absorption rate depends on how quickly the drug can move from the administration site into the bloodstream, which is largely determined by tissue perfusion (blood flow) and the distance the drug must diffuse. Inhalation delivers the drug across the alveolar membrane into a very well‑vascularized surface, so absorption is rapid. Rectal administration also provides good vascular access through the mucosa, leading to relatively quick uptake (though it can be variable). Peritoneal administration involves the richly perfused peritoneal membranes, allowing relatively fast absorption as well. Subcutaneous administration, on the other hand, places the drug in fatty connective tissue with limited blood flow and greater diffusion distance, creating a depot effect that slows entry into the bloodstream. Therefore, the slowest rate of absorption among these routes is subcutaneous.

In which of the following routes of administration, would a drug have the slowest rate of absorption into the bloodstream?

Prepare for the AALAS LATG Test. Study with interactive flashcards and detailed multiple-choice questions, each with hints and explanations. Achieve your certification goals!

In which of the following routes of administration, would a drug have the slowest rate of absorption into the bloodstream?

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